After Windows update KB4338815, the Lasernet Developers "Update" function will not work anymore.

Every time a user clicks on Update,  neither do the services respond nor can they be stopped in Task Manager.

1. Reboot the machine every time you make an update.

After you install any of the July 2018 .NET Framework Security Updates, a COM component fails to load because of “access denied,” “class not registered,” or “internal failure occurred for unknown reasons” errors.

The most common failure signature is the following:

Exception type: System.UnauthorizedAccessException

Message: Access is denied. (Exception from HRESULT: 0x80070005 (E_ACCESSDENIED))

2. For more information on a resolution to this, please see KB 4345913.
 
 After installing KB4346745, the error will not occur.